Pharmacokinetics
Absorption
Topical steroids can be absorbed from intact skin. Occlusive dressings, inflammation, and other
disease processes in the skin increase percutaneous absorption of topical steroids.
Distribution
Once absorbed, corticosteroids are variably bound to plasma protein.
Metabolism
Corticosteroids are metabolized primarily in the liver.
Elimination
Corticosteroids are excreted primarily by the kidneys and to varying amounts into the bile.
Indications and Usage
Relief of inflammation and pruritus caused by corticosteroid-responsive dermatoses.
Contraindications
Standard considerations.
Dosage and Administration
Adults and Children Topical Apply thin film to affected area twice daily to 3 times daily.
General Advice
- For topical use only. Not for ophthalmic, oral, or intravaginal use.
- Do not apply to face, groin, or axillae unless directed by health care provider.
- Apply medication sparingly but in sufficient quantity to cover affected area(s); rub in gently.
- If using solution on scalp, part the hair, apply a small amount of the medicine on the affected area, rub it in gently, and protect the area from washing and rubbing until the solution dries. Advise patient that they may wash hair as usual but not immediately after applying the medicine.
- Avoid contact with the eyes. If medication does come into contact with the eyes, wash them with large amounts of cool water.
